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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
24.55
Human Site:
Y450
Identified Species:
45
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
Y450
K
N
P
V
T
G
N
Y
V
K
M
S
L
Q
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
Y446
K
N
P
V
T
S
T
Y
S
K
M
S
L
Q
L
Dog
Lupus familis
XP_546691
722
81319
Y620
K
N
P
V
T
G
N
Y
V
K
M
S
L
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
Y450
K
N
P
V
T
G
N
Y
V
K
M
S
L
Q
L
Rat
Rattus norvegicus
Q09137
552
62239
Y450
K
N
P
V
T
G
N
Y
V
K
M
S
L
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
Y415
K
N
P
V
T
S
T
Y
S
K
M
S
L
Q
L
Chicken
Gallus gallus
Q9IA88
798
88848
H665
Q
R
M
L
Q
L
Q
H
H
Q
L
L
Q
P
A
Frog
Xenopus laevis
NP_001088426
560
64038
Y456
K
N
P
V
T
S
M
Y
T
K
M
S
L
Q
L
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
Q788
A
Q
T
L
P
Q
Q
Q
V
T
I
Q
V
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
Q413
W
H
L
G
I
R
S
Q
S
K
P
N
D
I
M
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
P514
P
D
A
P
A
A
D
P
P
K
M
S
L
Q
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
K433
E
I
M
T
E
V
L
K
A
L
Q
D
L
N
V
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
E521
Y
P
L
D
V
M
G
E
I
Y
I
A
L
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
80
100
N.A.
100
100
N.A.
80
0
80
13.3
N.A.
N.A.
6.6
40
N.A.
P-Site Similarity:
100
N.A.
80
100
N.A.
100
100
N.A.
80
33.3
80
33.3
N.A.
N.A.
33.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
0
0
8
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
8
0
0
0
0
8
8
0
0
% D
% Glu:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
31
8
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
8
0
16
0
0
8
0
% I
% Lys:
54
0
0
0
0
0
0
8
0
70
0
0
0
8
0
% K
% Leu:
0
0
16
16
0
8
8
0
0
8
8
8
77
0
62
% L
% Met:
0
0
16
0
0
8
8
0
0
0
62
0
0
0
8
% M
% Asn:
0
54
0
0
0
0
31
0
0
0
0
8
0
8
8
% N
% Pro:
8
8
54
8
8
0
0
8
8
0
8
0
0
8
0
% P
% Gln:
8
8
0
0
8
8
16
16
0
8
8
8
8
70
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
24
8
0
24
0
0
62
0
0
0
% S
% Thr:
0
0
8
8
54
0
16
0
8
8
0
0
0
0
0
% T
% Val:
0
0
0
54
8
8
0
0
39
0
0
0
8
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
54
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _